Targeted Network Meeting
Common mechanisms and therapeutic avenues for Down syndrome and other genetic developmental disorders

coordinators: Marie-Claude Potier, France
Mara Dierssen, Spain
Wednesday 21 September 2016

08:00 - 15:00

Hall M2
08:00 - 09:30 Down syndrome and other genetic developmental disorders: common mechanisms
 chair: Renata Bartesaghi, Italy
08:00 - 08:30Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes
 speaker: Victor Faundez, United States
08:30 - 09:00Fragile X syndrome: from molecular pathology to therapy
 speaker: Barbara Bardoni, France
09:00 - 09:30New perspectives for the rescue of cognitive disability in Down syndrome
 speaker: Renata Bartesaghi, Italy
09:30 - 09:45Discussion
09:45 - 10:15Break
10:15 - 11:45Challenges and opportunities for clinical trials
 chair: Rafael de la Torre Fornell, Spain
10:15 - 10:45Recent advances in the pharmacology of neurodevelopmental disorders
 speaker: Hanns Möhler, Switzerland
10:45 - 11:15Translating molecular advances in Down syndrome and in fragile X syndrome into therapy
 speaker: Rafael de la Torre Fornell, Spain
11:15 - 11:45Computational methods to unravel the pathophysiology in Down syndrome
 speaker: Mara Dierssen, Spain
11:45 - 12:00Discussion
12:00 - 13:00Lunch
13:00 - 14:30Down syndrome and other genetic developmental disorders: new avenues
 chair: Dean Nizetic, Singapore
13:00 - 13:30Boosting plasticity through neurorehablilitation with magnetic/electric stimulation and cognitive training
 speaker: Roi Cohen Kadosh, United Kingdom
13:30 - 14:00Modelling Down syndrome in iPSCs
 speaker: Dean Nizetic, Singapore
14:00 - 14:30Mouse models and development of DS therapeutics
 speaker: Yann Herault, France
14:30 - 14:45Discussion
14:45 - 15:00General discussion and closing